Microwave-assisted solid-phase synthesis of hydantoin derivatives
نویسندگان
چکیده
منابع مشابه
Microwave-assisted solid-phase synthesis of peptoids.
Microwave irradiation reduces the reaction time for the solid-phase synthesis of peptoids. Under these conditions, coupling of each residue requires only 1 min. The purity and yields of peptoids synthesized in this way are as good as or better than those achieved using standard methods. [reaction: see text]
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The high commercial demand for quinoxalines needs a rapid, greener and safer synthetic method among the chemists. A series of quinoxaline derivatives has been synthesized by condensation of diamines and dicarboniles in microwave heating conditions and in solvent free media. This environmentally benign synthetic approach gives us excellent yields (80-90%) in shorter reaction time (3.5 minutes.)....
متن کاملMicrowave assisted synthesis of novel functionalized hydantoin derivatives and their conversion to 5-(Z) arylidene-4H-imidazoles.
2-(Alkyl-1-yl)-1H-imidazol-5(4H)-ones 5a-n were synthesized via nucleophilic substitution of the methylsulfanyl group of the corresponding 2-(methylthio)-1H-imidazol-5(4H)-ones 3a-c with suitably substituted secondary amines. The starting 2-thioxo- imidazolidin-4-ones 2a,2b were prepared by condensation of thiohydantoin and benzo[b]-thiophene-3-carbaldehyde or benzofuran-3-carbaldehyde under mi...
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ژورنال
عنوان ژورنال: Tetrahedron Letters
سال: 2007
ISSN: 0040-4039
DOI: 10.1016/j.tetlet.2007.05.084